Sekkei Bio Private Limited
Website:
sekkeibio.com
Job details:
Company Description
Sekkei Bio is an innovation-driven drug discovery company on a mission to reshape the future of human health. Operating from India's premier deep-tech ecosystem in Bengaluru, we are redefining pharmaceutical innovation by integrating deep science, engineering, and advanced computational platforms. Our AI-enabled discovery engine and RNA-driven therapeutic strategies allow us to design next-generation biologics and transform complex injectable therapies into patient-centric solutions. At Sekkei Bio, we build scalable, regulatory-ready technologies that bridge discovery and commercial reality. Innovation is at the core of everything we do.
Role Summary
The incumbent will be responsible for the development and optimization of drug product (DP) formulations, with a focus on stability, delivery, and manufacturability. The role involves pre-formulation studies, formulation development, and collaboration with cross-functional teams to enable successful scale-up and technology transfer. This is an excellent opportunity for an early career professional to contribute to innovative formulation strategies in a fast-paced R&D environment.
Key Responsibilities
Drug Product Formulation Development
• Develop and optimize drug product formulations for peptides, RNA, or small molecules
• Design formulations to enhance stability, bioavailability, and patient compliance
• Evaluate different delivery systems (e.g., oral, injectable, novel delivery platforms)
Pre-formulation Studies
• Conduct pre-formulation studies including solubility, stability, compatibility, and excipient screening
• Characterize physicochemical properties to guide formulation strategies
• Support selection of optimal formulation approaches
Stability Studies
• Design and execute stability studies under various storage conditions
• Monitor and analyze stability data to establish shelf life and storage requirements
• Identify degradation pathways and propose mitigation strategies
Scale-Up & Technology Transfer
• Support scale-up of formulations from lab to pilot scale
• Assist in technology transfer to manufacturing teams or external partners
• Ensure reproducibility and robustness of formulations during scale-up
Cross-Functional Coordination
• Collaborate closely with analytical teams for characterization and stability testing
• Work with process development and manufacturing teams to ensure seamless transition
• Support CMC documentation and development activities
Documentation & Compliance
• Maintain accurate experimental records in accordance with Good Documentation Practices (GDP)
• Prepare formulation development reports and technical documentation
• Ensure compliance with regulatory guidelines and internal SOPs
Candidate Profile
Qualification & Experience
• M.Pharm in Pharmaceutics or related field with 3-5 years of relevant industry experience
• Hands-on experience in drug product formulation and pre-formulation studies
• Understanding of stability studies and formulation optimization strategies
• Exposure to scale-up and technology transfer is preferred
• Familiarity with regulatory expectations and CMC documentation is a plus
- • Strong problem-solving, analytical, and communication skills
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