About the role
%3Cp%3E%3Coj-label class=%22block__field-label oj-label oj-component oj-complete%22 style=%22-webkit-text-stroke-width:0px;background-color:rgb(255, 255, 255);color:rgb(132, 132, 132);display:block;font-family:%26quot;Open Sans%26quot;, %26quot;Segoe UI%26quot;, Frutiger, %26quot;Frutiger Linotype%26quot;, %26quot;Dejavu Sans%26quot;, %26quot;Helvetica Neue%26quot;, Arial, sans-serif;font-size:0.929rem;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:normal;margin-bottom:0.25em;orphans:2;overflow-wrap:break-word;text-align:start;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;white-space:normal;widows:2;word-break:break-word;word-spacing:0px;%22 data-bind=%22attr: {for: %24data.name + %27-value%27, style : %24data.labelStyle }%22 for=%22descriptionExt-value%22 id=%22ui-id-44524%22%3E%3C/oj-label%3E%3C/p%3E%3Cdiv class=%22oj-form-control block__field-rtfValue %22 style=%22-webkit-text-stroke-width:0px;background-color:rgb(255, 255, 255);color:rgb(0, 0, 0);font-family:%26quot;Open Sans%26quot;, %26quot;Segoe UI%26quot;, Frutiger, %26quot;Frutiger Linotype%26quot;, %26quot;Dejavu Sans%26quot;, %26quot;Helvetica Neue%26quot;, Arial, sans-serif;font-size:13.02px;font-style:normal;font-variant-caps:normal;font-variant-ligatures:normal;font-weight:400;letter-spacing:normal;margin-bottom:5px;orphans:2;padding-bottom:5px;text-align:start;text-decoration-color:initial;text-decoration-style:initial;text-decoration-thickness:initial;text-indent:0px;text-transform:none;vertical-align:middle;white-space:normal;widows:2;word-spacing:0px;%22 data-bind=%22attr: {id: %24data.name + %27-value%27, formFieldId: %24data.name},%0A html: %24component.getFieldValue(%24data)%22 id=%22descriptionExt-value%22 formfieldid=%22descriptionExt%22%3E%3Cp%3E%26nbsp;%3C/p%3E%3Cp%3E%3Cstrong%3EWHY UT SOUTHWESTERN?%3C/strong%3E%3Cbr%3EWith over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. As a world-renowned medical and research center, we strive to provide the best possible care, resources, and benefits for our valued employees. Ranked as the number 1 hospital in Dallas-Fort Worth according to %3Ca style=%22color:rgb(4, 95, 171);line-height:inherit;text-decoration:none;%22 href=%22https://www.utsouthwestern.edu/newsroom/articles/year-2022/july-us-news-best-hospital.html%22 target=%22_blank%22%3EU.S. News %26amp; World Report%3C/a%3E, we invest in you with opportunities for career growth and development to align with your future goals. Our highly competitive benefits package offers healthcare, PTO and paid holidays, on-site childcare, wage, merit increases and so much more. We invite you to be a part of the UT Southwestern team where you%27ll discover a culture of teamwork, professionalism, and a rewarding career!%3C/p%3E%3Cp%3E%3Cbr%3E%3Cstrong%3EJOB SUMMARY%3C/strong%3E%3Cbr%3E%3Cbr%3EWe are currently looking for an enthusiastic, scientifically curious researcher to work in the laboratory of Dr. Deepak Nijhawan, Professor, Vice Chair of Research and Chief of Molecular Medicine in the Department of Radiation Oncology. %26nbsp;The research program in the Nijhawan lab involves a collaborative approach to understand the mechanism of action for small molecules with interesting biologic activity, identify their molecular targets, and to explore the therapeutic potential of novel compounds. The lab mission is focused on translational opportunities relevant to human disease, with a keen interest in identifying novel cancer therapeutics.%26nbsp;%3Cbr%3E%3Ca href=%22https://labs.utsouthwestern.edu/nijhawan-de-brabander-lab%22%3Ehttps://labs.utsouthwestern.edu/nijhawan-de-brabander-lab%3C/a%3E%3C/p%3E%3Cp%3EWe are seeking highly organized and proactive individuals to join our multi-disciplinary team. %26nbsp;Positions are available in several areas including focuses on molecular biology and biochemistry or on in vivo studies to support the preclinical development of novel compounds. The ideal candidate would be self-motivated and possess strong initiative to problem solve and to trouble shoot experimental or technical issues. It is essential that the candidate pay close attention to details and be able to keep careful records of experiments and results. Strong organizational skills, prioritization skills, and time management skills are a must. It will also be important for the candidate to work efficiently and to be able to adapt to changing priorities. Candidates who are eager to learn and be part of a fast-paced research environment will be given the strongest consideration.%3C/p%3E%3Cp%3E%26nbsp;%3C/p%3E%3Cp style=%22margin:0px 0px 12px;%22%3E%3Cstrong%3EBENEFITS%3C/strong%3E%3Cbr%3EUT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:%3C/p%3E%3Cul style=%22margin:12px 0px;padding:revert;%22%3E%3Cli style=%22line-height:1.25;%22%3EPPO medical plan, available day one at no cost for full-time employee-only coverage%3C/li%3E%3Cli style=%22line-height:1.25;%22%3E100% coverage for preventive healthcare-no copay%3C/li%3E%3Cli style=%22line-height:1.25;%22%3EPaid Time Off, available day one%3C/li%3E%3Cli style=%22line-height:1.25;%22%3ERetirement Programs through the Teacher Retirement System of Texas (TRS)%3C/li%3E%3Cli style=%22line-height:1.25;%22%3EPaid Parental Leave Benefit%3C/li%3E%3Cli style=%22line-height:1.25;%22%3EWellness programs%3C/li%3E%3Cli style=%22line-height:1.25;%22%3ETuition Reimbursement%3C/li%3E%3Cli style=%22line-height:1.25;%22%3EPublic Service Loan Forgiveness (PSLF) Qualified Employer%3C/li%3E%3Cli style=%22line-height:1.25;%22%3E%3Ca style=%22color:rgb(4, 95, 171);line-height:inherit;text-decoration:none;%22 href=%22http://jobs.utsouthwestern.edu/benefits/#top%22 target=%22_blank%22%3ELearn more about these and other UTSW employee benefits!%3C/a%3E%3C/li%3E%3C/ul%3E%3Cp%3E%26nbsp;%3C/p%3E%3Cp%3E%3Cstrong%3EEXPERIENCE AND EDUCATION%3C/strong%3E%3Cbr%3E%3Cbr%3E%3Cstrong%3ERequired%3C/strong%3E%3C/p%3E%3Cul style=%22margin-bottom:12px;margin-right:0px;margin-top:12px;padding:revert;%22%3E%3Cli style=%22line-height:1.25;%22%3E%3Cp style=%22margin-left:0px;%22%3E%3Cstrong%3EEducation%3C/strong%3E%3Cbr%3EBachelor%27s Degree With major coursework in field of assignment and no experience%26nbsp;%3Cbr%3E%26nbsp;%3C/p%3E%3C/li%3E%3C/ul%3E%3Cul style=%22margin:12px 0px;padding:revert;%22%3E%3Cli style=%22line-height:1.25;%22%3E%3Cp%3E%3Cstrong%3EExperience%3C/strong%3E%3Cbr%3ENo experience required with Bachelor%27s Degree%3Cbr%3E%26nbsp;%3C/p%3E%3Cp%3E%26nbsp;%3C/p%3E%3C/li%3E%3C/ul%3E%3Cp%3E%3Cstrong%3EJOB DUTIES%3C/strong%3E%3C/p%3E%3Cp%3EPrincipal Responsibilities:%3Cbr%3E•%26nbsp;%26nbsp;%26nbsp;%26nbsp;Design and perform molecular biology experiments, including plasmid construction, cloning, and mutagenesis.%3Cbr%3E•%26nbsp;%26nbsp;%26nbsp;%26nbsp;Generate and characterize CRISPR-edited cell lines for functional studies.%3Cbr%3E•%26nbsp;%26nbsp;%26nbsp;%26nbsp;Express and purify recombinant proteins using affinity and size-exclusion chromatography.%3Cbr%3E•%26nbsp;%26nbsp;%26nbsp;%26nbsp;Perform biochemical and biophysical assays to assess protein activity, stability, and interactions.%3Cbr%3E•%26nbsp;%26nbsp;%26nbsp;%26nbsp;Conduct probe binding and fluorescence-based assays (e.g., FP, FRET).%3Cbr%3E•%26nbsp;%26nbsp;%26nbsp;%26nbsp;Maintain accurate lab records, prepare reagents, assist with data analysis, and be open to regularly presenting the findings in lab meetings.%3Cbr%3E•%26nbsp;%26nbsp;%26nbsp;%26nbsp;Design, planning and execution of various in vivo studies to evaluate novel compounds in preclinical mouse experiments including pharmacokinetic studies, pharmacodynamic studies, and efficacy studies.%3Cbr%3E•%26nbsp;%26nbsp;%26nbsp;%26nbsp;Monitoring and analysis of in vivo studies including but not limited to tumor size, animal health condition, in vivo imaging, and flow cytometry analysis of tissues.%3Cbr%3E•%26nbsp;%26nbsp;%26nbsp;%26nbsp;Administer daily drug treatments to mice and record dosing.%3Cbr%3E•%26nbsp;%26nbsp;%26nbsp;%26nbsp;Assist with the maintenance, care, breeding and genomic screening of mice in laboratory mouse colonies.%3Cbr%3E•%26nbsp;%26nbsp;%26nbsp;%26nbsp;Tissue culture of mammalian cell lines and execution of standard in vitro molecular and biochemical assays.%3C/p%3E%3Cp%3E%3Cbr%3E%3Cstrong%3ESECURITY AND EEO STATEMENT%3C/strong%3E%3Cbr%3E%3Cbr%3E%3Cstrong%3ESecurity%3C/strong%3E%3Cbr%3EThis position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.%3Cbr%3E%3Cbr%3E%3Cstrong%3EEEO%3C/strong%3E%3Cbr%3EUT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.%3C/p%3E%3C/div%3E
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