Scientist - Molecular Biology

Aurigene Pharmaceutical Services Limited

Website: aurigeneservices.com
Job details:

About the Role

We are seeking a self-driven Scientist to lead and deliver end-to-end molecular biology projects in our NBE Services portfolio. You will design and execute strategies for engineered antibodies, enzymes, structural proteins, and mutant strains — supporting global drug discovery programs in a fast-paced CRO environment.

Key Responsibilities

• Design and execute molecular biology workflows for production of engineered antibodies, enzymes, structural/reagent proteins, and mutant strains
• Lead gene synthesis, cloning, vector design/swapping, antibody gene sequencing, and site-directed mutagenesis projects
• Generate CRISPR-based mutants in prokaryotic systems; perform sequence data analysis and validation
• Execute mRNA isolation, cDNA synthesis, and gene expression analysis using Real-Time PCR
• Support HCP/HCD estimation, data analysis, and protein engineering initiatives
• Oversee plasmid production and chromatographic purification (affinity, IEX, SEC)
• Manage microbial, yeast, and fungal strain engineering, including cell bank preparation and characterization
• Operate and optimize automation/high-throughput platforms (liquid handlers, robotic systems)
• Mentor and lead the molecular biology team; drive project planning, execution, and client communication
• Prepare technical reports, presentations, project proposals, and SOPs with minimal review
• Ensure 100% compliance with GLP/GMP, ALCOA+ data integrity, and lab safety standards

Must-Have Qualifications

• 6-10 years of hands-on industrial or advanced academic experience in molecular biology R&D
• Expertise in:

• Cloning (In-Fusion, Gibson, TOPO, ligation-based)

• Vector design, gene synthesis, mutagenesis, antibody sequencing

• CRISPR-based editing in prokaryotes

• RT-qPCR, mRNA/cDNA workflows, sequence analysis

• Mammalian/microbial cell culture and strain engineering

• SnapGene, Sequencher, Benchling, or equivalent bioinformatics tools

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