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Discovery Postdoctoral Fellow in Cancer Functional Genomics

Min Experience

0 years

Location

Basel (City), Switzerland

JobType

full-time

About the job

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About the role

We are thrilled to open applications for our Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program. Come join Novartis Biomedical Research as a Discovery Postdoctoral Fellow and be part of our team in the Oncology Drug Discovery (ODD) group in Basel, Switzerland. You will work on a project that aims at understanding the molecular mechanisms regulating the activity of specific lineage-specific transcription factors, and how they selectively exert their oncogenic functions. You will employ cutting-edge gene editing and functional genomics techniques to dissect the structure-function relationship of these oncogenes, how they can differently regulate transcription and respond to external stimuli in the context of cancer, and help elucidate mechanisms of resistance that may arise upon pharmacological treatment. As part of the Discovery Fellowship track of the Novartis Postdoctoral Fellowship Program, you will join our vibrant, dedicated postdoctoral community for events, including the monthly postdoc seminars and other scheduled events for postdocs. Fellows are surrounded by a supportive, collaborative community of postdocs and scientists, who would contribute to the acceleration of your scientific growth, along with building your professional skillset, e.g. you will have the opportunity to do a Postdoc Practicum in another laboratory or in a business function of Novartis. This applied research program is up to 3 years in length, with the option of applying for an extension of up to 1 year. Discovery Postdoctoral Fellows have a unique opportunity to conduct innovative, interdisciplinary research and are expected to publish their results in leading journals. We collaborate across scientific and organizational boundaries, with a focus on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. Through the Novartis Postdoctoral Fellowship Program, you will build your competency as a drug hunter, and as a scientific leader in the field. You will join a professional network that will support your growth as a research scientist, and you will have the opportunity to tackle disease and make an impact, by reimagining medicine together.

About the company

Novartis is a global healthcare company based in Switzerland that provides solutions to address the evolving needs of patients worldwide.

Skills

gene regulation
chromatin
transcription factor biology
cancer
molecular biology tools
gene editing
genome-wide genomics techniques
ChIP-seq
ATAC-seq
functional genomics screens
CRISPR screen
Perturb-seq
deep mutational scanning
bioinformatics