Duties and Responsibilities:
It is everyone’s responsibility to live out our Values and Absolutes by Shaping a World of Trust while ensuring responsible progress.
• Perform precise and accurate sample preparation, including weighing, diluting, extraction and purifying samples for various analytical techniques.
• Develop, validate and document standard operating procedures for sample handling, ensuring consistency and repeatability in all preparation activities.
• Maintain detailed records and logs of all sample preparation steps, calculations and observations, supporting data integrity and traceability
• Collect, record and organize experimental data, conduct basic analyses to interpret results and support ongoing laboratory research
• Use of general laboratory equipment including but not limited to pipettors, centrifuges, incubators, biological safety cabinets and balances
• Perform RNA Sample preparation and gel electrophoresis
• Follow instruction and perform instrumental analysis on instruments including but not limited to AKTA, LC-MS, HPLC/UPLC, LTQ, QDA, CAD, Circular Dichroism, Karl Fischer titration, UV-vis/ Fluorescence spectrophotometers, thermal cycler, Nanodrop, SoloVPE instruments, etc. Provide basic troubleshooting to mentioned instrument.
• Instrument maintenance - MS and LC (pressure, column, etc) and troubleshooting LC/MS issues as they arise
• Work closely with members of the RNAi chemistry team to understand and validate requirements for oligonucleotide analytical control.
• Hands-on and independent lab experience with concentration calculation and unit conversion, buffer preparation, solution preparation, separation, quantification of DNA/RNA, oligonucleotides, etc.
• Software includes instrument-specific for capturing and analyzing data, Microsoft Office (Word, Excel, PowerPoint, Outlook, Teams/SharePoint, GraphPad Prism, Spotfire, etc), LIMS, electronic laboratory notebooks, etc.
• Detailed record keeping of daily experiments in ELNs
• General lab maintenance and Inventory management
• Follow the guidelines set forth with clients and Company Quality, Health, Safety, Security and Environmental policies and procedures.
• Comply with clients’ and Company management systems in accordance with appropriate regulatory agencies.
• Perform other essential tasks projects and responsibilities as required.
• Other duties as defined by the Manager, department needs and workload