Principal Data Scientist

We are seeking a Principal AI Platform Architect—Amgen's most senior individual-contributor authority on building and scaling end-to-end machine-learning and generative-AI platforms. Sitting at the intersection of engineering excellence and data-science enablement, you will design the core services, infrastructure and governance controls that allow hundreds of practitioners to prototype, deploy and monitor models—classical ML, deep learning and LLMs—securely and cost-effectively. Acting as a "player-coach," you will establish platform strategy, define technical standards, and partner with DevOps, Security, Compliance and Product teams to deliver a frictionless, enterprise-grade AI developer experience. Roles & Responsibilities: Define and evangelise the multi-year AI-platform vision, architecture blueprints and reference implementations that align with Amgen's digital-transformation and cloud-modernization objectives. Design and evolve foundational platform components—feature stores, model-registry, experiment-tracking, vector databases, real-time inference gateways and evaluation harnesses—using cloud-agnostic, micro-service principles. Implement robust MLOps pipelines (CI/CD for models, automated testing, canary releases, rollback) and enforce reproducibility from data ingestion to model serving. Embed responsible-AI and security-by-design controls—data-privacy, lineage tracking, bias monitoring, audit logging—through policy-as-code and automated guardrails. Serve as the ultimate technical advisor to product squads: codify best practices, review architecture/PRs, troubleshoot performance bottlenecks and guide optimisation of cloud resources. Partner with Procurement and Finance to develop TCO models, negotiate enterprise contracts for cloud/AI infrastructure, and continuously optimise spend. Drive platform adoption via self-service tools, documentation, SDKs and internal workshops; measure success through developer NPS, time-to-deploy and model uptime SLAs. Establish observability frameworks—metrics, distributed tracing, drift detection—to ensure models remain performant, reliable and compliant in production. Track emerging technologies (serverless GPUs, AI accelerators, confidential compute, policy frameworks like EU AI Act) and proactively integrate innovations that keep Amgen at the forefront of enterprise AI.

Amgen harnesses the best of biology and technology to fight the world's toughest diseases, and make people's lives easier, fuller and longer. We discover, develop, manufacture and deliver innovative medicines to help millions of patients. Amgen helped establish the biotechnology industry more than 40 years ago and remains on the cutting-edge of innovation, using technology and human genetic data to push beyond what's known today.