Flag job

Report

Scientist - Cheminformatics, Computational Chemistry

Location

Hyderabad, India

JobType

full-time

About the job

Info This job is sourced from a job board

About the role

Join us and contribute to the discovery of medicines that will impact lives! Work with R&D teams of our Biopharma clients, and collaborate with a team of Biologists, Medicinal Chemists, Computational Biologists, Data Scientists, Data Engineers, Web Developers, Cloud Engineers, and Solution Architects to create the next generation of innovative computational chemistry solutions for target discovery and validation. Identify areas of application for AI in Chemistry and related Lifesciences, and develop novel algorithms to drive data-driven drug discovery Drive lead discovery projects by proposing a testable hypothesis Apply the latest advances and develop methods for data mining and performing analysis of large datasets Investigate statistical approaches for analysis of High Throughput Screening (HTS) data Participate in collecting, quality control, normalization, modeling, and other such detailed analyses of specific HTS and/or 'omics data sets Development of processes and customizable workflows that can be adapted and applied across the portfolio Implement compound library design, QSAR, docking, virtual screening, molecular fragmentation, structure-based drug design, pharmacophore generation, and analysis, or multi-parameter optimization Leverage structure-based and ligand-based design techniques like protein modeling, virtual screening, QSAR, molecular dynamics simulations

About the company

Accelerate drug discovery and development for Biopharma and Biotech R&D with in silico solutions leveraging Computational Biology & Chemistry, High throughput Sciences, AI, ML, HPC, Cloud, Data, and DevOps. In silico solutions are transforming the biopharma and biotech industries. Our cross-domain science and technology team of experts embark upon and industrialize this transformation. We continually expand our world-class multi-disciplinary team in Genomics, AI, and Cloud computing, accelerating drug discovery and development. What drives us is the joy of working in an innovation-rich, research-powered startup bridging multiple disciplines to bring medicines faster for human use. We are working with several innovative Biopharma companies and expanding our client base globally. Read about how and what solutions we build. Aganitha (अगणित): "countless" or "limitless" in Sanskrit serves as a reminder and inspiration about the limitless potential in each one of us. Come join us to bring out your best and be limitless!

Skills

DFT
QM/MM
Cheminformatics
computational chemistry software
protein structure viewers
ChemAxon toolkits
RDKit
KNIME
open-source and proprietary databases
ChEMBL
PubChem
PDB
Uniprot
AlphaFoldDB
Dotmatics
LiveDesign
OpenTargets
data mining platforms
Spotfire
R shiny
Stardrop
virtual screening
docking
de novo design
compound redesign
optimization
molecular dynamics simulation
Markov State Models
free energy perturbation
QSAR
DMPK models